Malcom Bright knows how killers think and how their minds work, because his father, Dr. Martin Whilty, was one of the most notorious serial killers, called "The Surgeon." Alongside his longtime mentor, Gil Arroyo, and detectives Dani Powell and JT Tarmel, he helps the NYPD solve crimes by profiling killers, while also dealing with a manipulative mother, Jessica Whilty, an annoyingly normal sister, Ainsley Whilty and a homicidal father still looking to bond with his prodigal son.
Bright jumps at the chance to help Arroyo solve a quadruple homicide for the NYPD. As Bright slips into the mind of this serial killer, he finds himself dealing with the repercussions of seeing his father for the first time in years. Tormented by the terrors of his childhood, Bright is faced with a question: are his dreams just nightmares or did they actually happen?
A drug-induced homicide forces Malcolm to rethink his fears. Gil, Jessica and Ainsley catch wind that Malcolm has been seeing his father again.
As Malcolm's childhood memories surface, he realizes his father's killing spree may not have been a surprise to everyone in the family; Malcolm, Gil, Dani and JT hunt for a stalker with a creepy eye for design.
Malcolm searches the depths of his mind to unravel the mystery of "the girl in the box," but with his night terrors and lack of sleep increasing, his real life becomes more and more of a blur. When the NYPD investigates a homicide they assume is linked to a drug cartel, Malcolm discovers a secret about Dani's past that draws them closer together.